Activity record

PGDB_A058657

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

Dmax = 86 %

TargetNEK7
Cell lineCAL-51
ConcentrationConcentration series: 1 uM, 0.05 nM
Time24 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS002061
PatentWO2025024521A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020414
Compound IDPGDB_C020414
Compound241
Source record IDPGDB_C020414
InChIKeyAQSAMGJAVZWHNR-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002061
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
ConcentrationConcentration series: 1 uM, 0.05 nM
Treatment time24 h
TargetNEK7
E3Not specified
Cell lineCAL-51
OrganismHomo sapiens

Source evidence

Patent IDWO2025024521A1
Activity table
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