Activity record

PGDB_A059676

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 0.6 nM

TargetGSPT1
Cell lineNB4
Time6 d
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS002407
PatentWO2025146129A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C003359
Compound IDPGDB_C003359
Compound27;27
Source record IDPGDB_C003359
InChIKeyZPPJNQYGOWERRZ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002407
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time6 d
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineNB4

Source evidence

Patent IDWO2025146129A1
Compound location

27;27

27;27 enlarged structure27;27 location on patent page 16
Activity table
Page 56 · table start
Page 57 · table end