Search Browse Statistics Contact Help

·

SIMM · NJU

Loading activity

Loading detail record from the SQLite release...

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU

Contact us

Search Browse Statistics Contact Help

·

SIMM · NJU

Activity record

PGDB_A060263

Assay: % DegradationTarget: IKZF3QC: standardized

Activity overview

degradation >= 20 %

TargetIKZF3

ConcentrationConcentration series: 500 nM, 50 nM

Time24 h

Assay / ReadoutWestern_blot / percent_remaining

Assay IDPGDB_AS002465

PatentWO2025016359A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C019391

CompoundGT-06264

Source record IDPGDB_C019391

InChIKeySEYSDYDCMDAUHQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002465

Assay family% Degradation

Assay systemcell_based

Readoutpercent_remaining

TechnologyWestern_blot

ConcentrationConcentration series: 500 nM, 50 nM

Treatment time24 h

Detection targetprotein_degradation

TargetIKZF3

E3Not specified

OrganismHomo sapiens

Source evidence

Patent IDWO2025016359A1

Compound location

GT-06264

GT-06264 enlarged structure

GT-06264 location on patent page 50

Activity table

Page 201 · table start

Page 202 · table middle

Page 203 · table middle

Page 204 · table middle

Page 205 · table middle

Page 206 · table middle

Page 207 · table middle

Page 208 · table middle

Page 209 · table middle

Page 210 · table middle

Page 211 · table middle

Page 212 · table middle

Page 213 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU