Activity record

PGDB_A060969

Assay: viabilityTarget: PTPN11QC: standardized
Activity overview

IC50 = 500-1000 nM

TargetPTPN11
Cell lineHCC827
Assay / ReadoutCCK-8 / viability
Assay IDPGDB_AS001114
PatentCN116239566A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C025828
Compound IDPGDB_C025828
CompoundGT-03335
Source record IDPGDB_C015998
InChIKeyUCJZOKGUEJUNIO-IINYFYTJSA-N

Assay context

Assay IDPGDB_AS001114
Assay familyviability
Assay systemcell_based
Readoutviability
TechnologyCCK-8
Detection target% Cell viability
TargetPTPN11
E3Not specified
Cell lineHCC827
OrganismHomo sapiens

Source evidence

Patent IDCN116239566A
Compound location

GT-03335

GT-03335 enlarged structureGT-03335 location on patent page 843
Activity table
Page 847 · table single