Activity record

PGDB_A060984

Assay: % DegradationTarget: SALL4QC: standardized
Activity overview

DC50 > 10 uM

TargetSALL4
Cell lineHT-1080
Time20 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS002491
PatentEP4393915A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007561
Compound IDPGDB_C007561
Compound化合物17
Source record IDPGDB_C007561
InChIKeyQHKCMVCSYFSAEF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002491
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time20 h
Detection targetprotein_degradation
TargetSALL4
E3Not specified
Cell lineHT-1080

Source evidence

Patent IDEP4393915A1
Compound location

化合物17

化合物17 enlarged structure化合物17 location on patent page 112
Activity table
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