Activity record

PGDB_A061501

Assay: % DegradationTarget: CSNK1A1QC: ambiguous
Activity overview

DC50 = 2.8 nM

TargetCSNK1A1
Cell lineNCI-H1155
Time72 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS002387
PatentWO2024059107A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002846
Compound IDPGDB_C002846
Compound95;95;95
Source record IDPGDB_C002846
InChIKeyNBFAWLWAYOGJOI-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002387
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time72 h
TargetCSNK1A1
E3Not specified
Cell lineNCI-H1155

Source evidence

Patent IDWO2024059107A1
Compound location

95;95;95

95;95;95 enlarged structure95;95;95 location on patent page 12
Activity table
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