Activity record

PGDB_A061979

Assay: % DegradationTarget: IKZF2QC: ambiguous
Activity overview

DC50 = 7 nM

TargetIKZF2
Cell lineNCI-H1155
Time72 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS002270
PatentWO2024059107A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002842
Compound IDPGDB_C002842
Compound91;91;91
Source record IDPGDB_C002842
InChIKeyNOGRJAPNDFXWLC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002270
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time72 h
TargetIKZF2
E3Not specified
Cell lineNCI-H1155

Source evidence

Patent IDWO2024059107A1
Compound location

91;91;91

91;91;91 enlarged structure91;91;91 location on patent page 12
Activity table
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