Activity record

PGDB_A062481

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 0.2 nM

TargetGSPT1
Cell lineJeKo-1
Time72 h
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS001490
PatentWO2023078410A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005297
Compound IDPGDB_C005297
Compound4-87;4-87;4-87;4-87;4-87
Source record IDPGDB_C005297
InChIKeyTWTZRLPVAZESNK-IAXKEJLGSA-N

Assay context

Assay IDPGDB_AS001490
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineJeKo-1
OrganismHomo sapiens

Source evidence

Patent IDWO2023078410A1
Compound location

4-87;4-87;4-87;4-87;4-87

4-87;4-87;4-87;4-87;4-87 enlarged structure4-87;4-87;4-87;4-87;4-87 location on patent page 6
Activity table
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