Activity record

PGDB_A063100

Assay: % DegradationTarget: IKZF3QC: ambiguous
Activity overview

DC50 > 10000 nM

TargetIKZF3
Time20 h
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS001695
PatentWO2025049840
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010129
Compound IDPGDB_C010129
Compound5
Source record IDPGDB_C010129
InChIKeyBZFKRKNRSDSSIV-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001695
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time20 h
TargetIKZF3
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025049840
Compound location

5

5 enlarged structure5 location on patent page 95
Activity table
Page 106 · table single