Activity record

PGDB_A063186

Assay: viabilityTarget: RBM39QC: ambiguous
Activity overview

IC50 = 500-1000 nM

TargetRBM39
Cell lineHCT116
Time72 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS000963
PatentWO2025189015A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C027663
Compound IDPGDB_C027663
Compound24;24
Source record IDPGDB_C011431
InChIKeyKNVTWZMXPNKIQF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000963
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time72 h
Detection target% Cell viability
TargetRBM39
E3Not specified
Cell lineHCT116
OrganismHomo sapiens

Source evidence

Patent IDWO2025189015A1
Compound location

24;24

24;24 enlarged structure24;24 location on patent page 122
Activity table
Page 165 · table start