Activity record

PGDB_A063241

Assay: % DegradationTarget: CDK2QC: standardized
Activity overview

DC50 = 13 nM

TargetCDK2
Cell lineHEK293
Time24 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001903
PatentWO2025224262A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011728
Compound IDPGDB_C011728
Compound144;144;144
Source record IDPGDB_C011728
InChIKeyKNVWWGVIZSEPEL-QHXYEOIWSA-N

Assay context

Assay IDPGDB_AS001903
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time24 h
TargetCDK2
E3Not specified
Cell lineHEK293
OrganismHomo sapiens

Source evidence

Patent IDWO2025224262A1
Compound location

144;144;144

144;144;144 enlarged structure144;144;144 location on patent page 22
Activity table
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