Activity record

PGDB_A063906

Assay: % DegradationQC: standardized
Activity overview

inhibition > 20 %

Cell lineMV-4-11
Time7 d
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS001761
PatentWO2020064002A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001722
Compound IDPGDB_C001722
CompoundCC-220;CC-220
Source record IDPGDB_C021442
InChIKeyIXZOHGPZAQLIBH-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001761
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Treatment time7 d
Detection target% Cell viability
E3CRBN
Cell lineMV-4-11
OrganismHomo sapiens

Source evidence

Patent IDWO2020064002A1
Compound location

CC-220;CC-220

CC-220;CC-220 enlarged structureCC-220;CC-220 location on patent page 5
Activity table
Page 198 · table single