Activity record

PGDB_A064866

Assay: viabilityTarget: IKZF3QC: ambiguous
Activity overview

inhibition = 30-40 %

TargetIKZF3
Cell lineMDA-MB-231
Concentration10 nM
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS000133
PatentWO2025016359A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019525
Compound IDPGDB_C019525
CompoundGT-08004
Source record IDPGDB_C019525
InChIKeyYADBQOLVMMFQHN-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000133
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration10 nM
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineMDA-MB-231
OrganismHomo sapiens

Source evidence

Patent IDWO2025016359A1
Compound location

GT-08004

GT-08004 enlarged structureGT-08004 location on patent page 56
Activity table
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