Activity record

PGDB_A065201

Assay: viabilityTarget: EGFRQC: standardized
Activity overview

IC50 = 1000-5000 nM

TargetEGFR
Cell lineNCI-H358
Assay / ReadoutCCK-8 / viability
Assay IDPGDB_AS000770
PatentCN116239566A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C025847
Compound IDPGDB_C025847
CompoundGT-03353
Source record IDPGDB_C016017
InChIKeyJCUTYXYQIGFGHQ-SVQMELKDSA-N

Assay context

Assay IDPGDB_AS000770
Assay familyviability
Assay systemcell_based
Readoutviability
TechnologyCCK-8
Detection target% Cell viability
TargetEGFR
E3Not specified
Cell lineNCI-H358
OrganismHomo sapiens

Source evidence

Patent IDCN116239566A
Compound location

GT-03353

GT-03353 enlarged structureGT-03353 location on patent page 307
Activity table
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