Activity record

PGDB_A065430

Assay: bindingTarget: CRBNQC: standardized
Activity overview

inhibition = 97.86 %

TargetCRBN
E3 ligaseCRBN
ConcentrationConcentration series: 50 uM, 100 uM
Time2 h
Assay / Readout% Inhibition / binding
Assay IDPGDB_AS001451
PatentCN121378270A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007377
Compound IDPGDB_C007377
Compound实施例4
Source record IDPGDB_C007377
InChIKeyDXLSSZBWXJRHSO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001451
Assay familybinding
Assay systemcell_based
Readout% Inhibition
ConcentrationConcentration series: 50 uM, 100 uM
Treatment time2 h
Detection targetcell_inhibition
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDCN121378270A
Compound location

实施例4

实施例4 enlarged structure实施例4 location on patent page 17
Activity table
Page 20 · table single