Activity record

PGDB_A065708

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 10-100 nM

TargetGSPT1
Cell lineKG-1
Time72 h
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS000854
PatentWO2024251301A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007915
Compound IDPGDB_C007915
Compound化合物 NX-2
Source record IDPGDB_C007915
InChIKeyBTUVJBOFQVOKLB-OGLMXYFKSA-N

Assay context

Assay IDPGDB_AS000854
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time72 h
TargetGSPT1
E3Not specified
Cell lineKG-1

Source evidence

Patent IDWO2024251301A1
Compound location

化合物 NX-2

化合物 NX-2 enlarged structure化合物 NX-2 location on patent page 14
Activity table
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