Activity record

PGDB_A066086

Assay: viabilityTarget: DDX5QC: ambiguous
Activity overview

IC50 = 14.91 nM

TargetDDX5
Cell lineMDA-MB-453
Time3 d
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001536
PatentAU2023256446A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C006029
Compound IDPGDB_C006029
CompoundPBX-7018
Source record IDPGDB_C006029
InChIKeySEAAWKIYCKSRNY-JTHLAKFHSA-N

Assay context

Assay IDPGDB_AS001536
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time3 d
Detection target% Cell viability
TargetDDX5
E3Not specified
Cell lineMDA-MB-453

Source evidence

Patent IDAU2023256446A1
Compound location

PBX-7018

PBX-7018 enlarged structurePBX-7018 location on patent page 99
Activity table
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