Activity record

PGDB_A066112

Assay: % DegradationTarget: IKZF1QC: ambiguous
Activity overview

Dmax = 88 %

TargetIKZF1
Cell lineNCI-H1155
Time72 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS002425
PatentWO2024059107A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002849
Compound IDPGDB_C002849
Compound98;98
Source record IDPGDB_C002849
InChIKeyPDSQZCRQLLEYQG-FVRDMJKUSA-N

Assay context

Assay IDPGDB_AS002425
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Treatment time72 h
TargetIKZF1
E3Not specified
Cell lineNCI-H1155
OrganismHomo sapiens

Source evidence

Patent IDWO2024059107A1
Compound location

98;98

98;98 enlarged structure98;98 location on patent page 12
Activity table
Page 142 · table single