Activity record

PGDB_A067133

Assay: viabilityTarget: GSPT1QC: ambiguous
Activity overview

IC50 = 0.47 nM

TargetGSPT1
Cell lineNCI-H1299
Time72 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002069
PatentCN120365257A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000738
Compound IDPGDB_C000738
Compound实施例 04;实施例04
Source record IDPGDB_C000738
InChIKeyJKJGHQUBWJKUOD-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002069
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineNCI-H1299

Source evidence

Patent IDCN120365257A
Compound location

实施例 04;实施例04

实施例 04;实施例04 enlarged structure实施例 04;实施例04 location on patent page 5
Activity table
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