Activity record

PGDB_A068065

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 12.9 nM

TargetGSPT1
Cell lineNB4
Time6 d
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS002407
PatentWO2025146129A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C003363
Compound IDPGDB_C003363
Compound31
Source record IDPGDB_C003363
InChIKeyAADVKMXXCYJNQQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002407
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time6 d
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineNB4

Source evidence

Patent IDWO2025146129A1
Compound location

31

31 enlarged structure31 location on patent page 16
Activity table
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