Search Browse Statistics Contact Help

·

SIMM · NJU

Loading activity

Loading detail record from the SQLite release...

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU

Contact us

Search Browse Statistics Contact Help

·

SIMM · NJU

Activity record

PGDB_A069478

Assay: % DegradationTarget: CSNK1A1QC: standardized

Activity overview

degradation >= 20 %

TargetCSNK1A1

ConcentrationConcentration series: 500 nM, 50 nM

Time24 h

Assay / ReadoutWestern_blot / percent_remaining

Assay IDPGDB_AS001449

PatentCN120548310A

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C000754

CompoundGT-04378

Source record IDPGDB_C000754

InChIKeyOBVWUQKZPMSVKT-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001449

Assay family% Degradation

Assay systemcell_based

Readoutpercent_remaining

TechnologyWestern_blot

ConcentrationConcentration series: 500 nM, 50 nM

Treatment time24 h

TargetCSNK1A1

E3Not specified

Source evidence

Patent IDCN120548310A

Compound location

GT-04378

GT-04378 enlarged structure

GT-04378 location on patent page 23

Activity table

Page 140 · table start

Page 141 · table middle

Page 142 · table middle

Page 143 · table middle

Page 144 · table middle

Page 145 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU