Activity record

PGDB_A069640

Assay: viabilityTarget: EGFRQC: standardized
Activity overview

IC50 = 50-100 nM

TargetEGFR
Cell lineHCC827
Assay / ReadoutCCK-8 / viability
Assay IDPGDB_AS002229
PatentCN116239566A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C025853
Compound IDPGDB_C025853
CompoundGT-03548
Source record IDPGDB_C016023
InChIKeySWSLZMGPLRKRIZ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002229
Assay familyviability
Assay systemcell_based
Readoutviability
TechnologyCCK-8
Detection target% Cell viability
TargetEGFR
E3Not specified
Cell lineHCC827
OrganismHomo sapiens

Source evidence

Patent IDCN116239566A
Compound location

GT-03548

GT-03548 enlarged structureGT-03548 location on patent page 317
Activity table
Page 847 · table start
Page 848 · table end