Activity record

PGDB_A070472

Assay: viabilityTarget: RBM39QC: ambiguous
Activity overview

IC50 = 500-1000 nM

TargetRBM39
Cell lineHCT116
Time72 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS000963
PatentWO2025189015A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C027674
Compound IDPGDB_C027674
Compound35;35
Source record IDPGDB_C011442
InChIKeyDYKWLHJGSFFUIT-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000963
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time72 h
Detection target% Cell viability
TargetRBM39
E3Not specified
Cell lineHCT116
OrganismHomo sapiens

Source evidence

Patent IDWO2025189015A1
Compound location

35;35

35;35 enlarged structure35;35 location on patent page 143
Activity table
Page 165 · table start