Activity record

PGDB_A070581

Assay: % DegradationTarget: IKZF2QC: standardized
Activity overview

degradation = 78.9 %

TargetIKZF2
Cell lineHEK293T
Concentration1 uM
Time24 h
Assay / Readoutfluorescence / % Degradation
Assay IDPGDB_AS000641
PatentUS20230265071A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000385
Compound IDPGDB_C000385
Compound15;15
Source record IDPGDB_C000385
InChIKeyXCINFRYXVWFEQQ-PFIFLBKHSA-N

Assay context

Assay IDPGDB_AS000641
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Technologyfluorescence
Concentration1 uM
Treatment time24 h
TargetIKZF2
E3Not specified
Cell lineHEK293T
OrganismHomo sapiens

Source evidence

Patent IDUS20230265071A1
Compound location

15;15

15;15 enlarged structure15;15 location on patent page 32
Activity table
Page 166 · table single