Activity record

PGDB_A071057

Assay: % DegradationTarget: IKZF2QC: standardized
Activity overview

degradation = 83 %

TargetIKZF2
Cell lineHL-60
Concentration10 nM
Time24 h
Assay / ReadoutWestern_blot / percent_remaining
Assay IDPGDB_AS000166
PatentWO2023116835A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000541
Compound IDPGDB_C000541
CompoundA80;A80;A80
Source record IDPGDB_C000541
InChIKeyPMUIBOGXXSNZKZ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000166
Assay family% Degradation
Assay systemcell_based
Readoutpercent_remaining
TechnologyWestern_blot
Concentration10 nM
Treatment time24 h
Detection targetprotein_degradation
TargetIKZF2
E3Not specified
Cell lineHL-60

Source evidence

Patent IDWO2023116835A1
Compound location

A80;A80;A80

A80;A80;A80 enlarged structureA80;A80;A80 location on patent page 59
Activity table
Page 141 · table single