Activity record

PGDB_A072497

Assay: viabilityTarget: IKZF3QC: ambiguous
Activity overview

inhibition = 30-40 %

TargetIKZF3
Cell lineMDA-MB-231
Concentration500 nM
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS000281
PatentWO2025016359A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019542
Compound IDPGDB_C019542
CompoundGT-07843
Source record IDPGDB_C019542
InChIKeyCTYVUAISGHYCIO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000281
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration500 nM
Detection targetcell_proliferation
TargetIKZF3
E3Not specified
Cell lineMDA-MB-231
OrganismHomo sapiens

Source evidence

Patent IDWO2025016359A1
Compound location

GT-07843

GT-07843 enlarged structureGT-07843 location on patent page 42
Activity table
Page 199 · table start
Page 200 · table end