Activity record

PGDB_A072610

Assay: viabilityTarget: IKZF3QC: standardized
Activity overview

inhibition = 50-60 %

TargetIKZF3
Cell lineMM.1S
Concentration500 nM
Time96 h
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS001942
PatentWO2025162225A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024523
Compound IDPGDB_C024523
CompoundGT-10621
Source record IDPGDB_C024523
InChIKeyLCUIYLIBPABGSX-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001942
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration500 nM
Treatment time96 h
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineMM.1S
OrganismHomo sapiens

Source evidence

Patent IDWO2025162225A1
Compound location

GT-10621

GT-10621 enlarged structureGT-10621 location on patent page 26
Activity table
Page 155 · table single