Activity record

PGDB_A074649

Assay: viabilityTarget: EGFRQC: standardized
Activity overview

IC50 < 50 nM

TargetEGFR
Cell lineNCI-H358
Assay / ReadoutCCK-8 / viability
Assay IDPGDB_AS000770
PatentCN116239566A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C025846
Compound IDPGDB_C025846
CompoundGT-03412
Source record IDPGDB_C016016
InChIKeyURWFAUCRWLPHOT-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000770
Assay familyviability
Assay systemcell_based
Readoutviability
TechnologyCCK-8
Detection target% Cell viability
TargetEGFR
E3Not specified
Cell lineNCI-H358
OrganismHomo sapiens

Source evidence

Patent IDCN116239566A
Compound location

GT-03412

GT-03412 enlarged structureGT-03412 location on patent page 306
Activity table
Page 847 · table start
Page 848 · table end