Activity record

PGDB_A075377

Assay: % DegradationTarget: KDM4BQC: ambiguous
Activity overview

DC50 = 40 nM

TargetKDM4B
Cell lineBE2C
Time24 h
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001721
PatentWO2025199151A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011575
Compound IDPGDB_C011575
Compound6
Source record IDPGDB_C011575
InChIKeyNWAAUFNIGHEKJT-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001721
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time24 h
TargetKDM4B
E3Not specified
Cell lineBE2C
OrganismHomo sapiens

Source evidence

Patent IDWO2025199151A1
Compound location

6

6 enlarged structure6 location on patent page 118
Activity table
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