Activity record

PGDB_A076254

Assay: % DegradationQC: standardized
Activity overview

IC50 = 0.25 uM

Cell lineMV-4-11
Time7 d
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS001761
PatentWO2020064002A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C004157
Compound IDPGDB_C004157
Compound164;164
Source record IDPGDB_C021598
InChIKeyXUXKSYSOBOXHAT-HMTLIYDFSA-N

Assay context

Assay IDPGDB_AS001761
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Treatment time7 d
Detection target% Cell viability
E3CRBN
Cell lineMV-4-11
OrganismHomo sapiens

Source evidence

Patent IDWO2020064002A1
Compound location

164;164

164;164 enlarged structure164;164 location on patent page 40
Activity table
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