Activity record

PGDB_A077287

Assay: % DegradationTarget: VAV1QC: manual_curated
Activity overview

DC50 <= 10 nM

TargetVAV1
Cell lineJurkat
Time24 h
Assay / ReadoutWestern_blot / DC50
Assay IDPGDB_AS001882
PatentWO2026041143A1
QC statusmanual_curated
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009247
Compound IDPGDB_C009247
Compound65
Source record IDPGDB_C009247
InChIKeyXCKISLUXDQVXLT-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001882
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
TechnologyWestern_blot
Treatment time24 h
Detection targetprotein_degradation
TargetVAV1
E3Not specified
Cell lineJurkat

Source evidence

Patent IDWO2026041143A1
Compound location

65

65 enlarged structure65 location on patent page 50
Activity table
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