Activity record

PGDB_A077385

Assay: % DegradationTarget: IKZF2QC: ambiguous
Activity overview

Dmax = 64 %

TargetIKZF2
Time13 d
Assay / Readoutflow_cytometry / Dmax
Assay IDPGDB_AS000562
PatentWO2025064197
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010133
Compound IDPGDB_C010133
Compound4
Source record IDPGDB_C010133
InChIKeyIPPKELHFNVYXKG-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000562
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyflow_cytometry
Treatment time13 d
Detection targetprotein_degradation
TargetIKZF2
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025064197
Compound location

4

4 enlarged structure4 location on patent page 83
Activity table
Page 92 · table single