Activity record

PGDB_A077612

Assay: viabilityTarget: IKZF3QC: standardized
Activity overview

inhibition = 40-50 %

TargetIKZF3
Cell lineCFPAC-1
Concentration500 nM
Time96 h
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS000857
PatentWO2025162225A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024438
Compound IDPGDB_C024438
CompoundGT-10548
Source record IDPGDB_C024438
InChIKeyZAVGAEVDJPXVNC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000857
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration500 nM
Treatment time96 h
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineCFPAC-1
OrganismHomo sapiens

Source evidence

Patent IDWO2025162225A1
Compound location

GT-10548

GT-10548 enlarged structureGT-10548 location on patent page 28
Activity table
Page 156 · table single