Activity record

PGDB_A077623

Assay: % DegradationQC: standardized
Activity overview

DC50 < 100 nM

Cell line293T.114
TimeDC50 > 10000 nM | Emax < 45%
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001201
PatentWO2022081927A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C026764
Compound IDPGDB_C026764
Compound{4499}
Source record IDPGDB_C026795
InChIKeyUHSKQRUYOQORDF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001201
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment timeDC50 > 10000 nM | Emax < 45%
TargetGSPT1
E3Not specified
Cell line293T.114
OrganismHomo sapiens

Source evidence

Patent IDWO2022081927A1
Activity table
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