Activity record

PGDB_A078969

Assay: viabilityTarget: KRASQC: ambiguous
Activity overview

IC50 > 1000 nM

TargetKRAS
Cell lineNCI-H727
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS000308
PatentWO2026114957A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031940
Compound IDPGDB_C031940
CompoundEx.156*
Source record IDPGDB_C031940
InChIKeyIQXCYAVKVWJTRV-DXYQNXQJSA-N

Assay context

Assay IDPGDB_AS000308
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Detection target% Cell viability
TargetKRAS
E3Not specified
Cell lineNCI-H727
OrganismHomo sapiens

Source evidence

Patent IDWO2026114957A1
Compound location

Ex.156*

Ex.156* enlarged structureEx.156* location on patent page 163
Activity table
Page 163 · table single