Activity record

PGDB_A079100

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 18.7 nM

E3 ligaseCRBN
Cell lineAsPC-1
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000561
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031983
Compound IDPGDB_C031983
CompoundI-44;I-44
Source record IDPGDB_C031983
InChIKeyXOLAPTZDOBBGKH-CLKVLONXSA-N

Assay context

Assay IDPGDB_AS000561
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineAsPC-1
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-44;I-44

I-44;I-44 enlarged structureI-44;I-44 location on patent page 282
Activity table
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