Activity record

PGDB_A079355

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 0.3 nM

E3 ligaseCRBN
Cell lineSW620
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001786
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031948
Compound IDPGDB_C031948
CompoundI-8;I-8
Source record IDPGDB_C031948
InChIKeyRUUQMNFANMRJDY-JROJCBTDSA-N

Assay context

Assay IDPGDB_AS001786
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineSW620
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-8;I-8

I-8;I-8 enlarged structureI-8;I-8 location on patent page 248
Activity table
Page 300 · table start
Page 301 · table end