Activity record

PGDB_A081833

Assay: biochemicalTarget: VAV1QC: ambiguous
Activity overview

EC50 < 100 nM

TargetVAV1
E3 ligaseCRBN
Assay / ReadoutHTRF / EC50
Assay IDPGDB_AS000672
PatentWO2026119245A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C032077
Compound IDPGDB_C032077
Compound实施例 4
Source record IDPGDB_C032077
InChIKeyXCXGIHAPKFGVCC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000672
Assay familybiochemical
Assay systembiochemical
ReadoutEC50
TechnologyHTRF
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDWO2026119245A1
Compound location

实施例 4

实施例 4 enlarged structure实施例 4 location on patent page 38
Activity table
Page 63 · table single