PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

119 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

TargetKRAS

E3Not specified

Detection targetprotein_degradation

Activity compounds and values

Activity records

119 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	=	70	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A007716	PGDB_C006241	PGDB_AS002434	View
% Degradation	-	=	20	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A008281	PGDB_C006276	PGDB_AS002434	View
% Degradation	-	=	70	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A009327	PGDB_C006235	PGDB_AS002434	View
% Degradation	-	=	50	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A012425	PGDB_C006279	PGDB_AS002434	View
% Degradation	-	=	15	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A012719	PGDB_C006193	PGDB_AS002434	View
% Degradation	-	=	75	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A012768	PGDB_C006242	PGDB_AS002434	View
% Degradation	-	=	52	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A013783	PGDB_C006190	PGDB_AS002434	View
% Degradation	-	=	2	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A014000	PGDB_C006185	PGDB_AS002434	View
% Degradation	-	=	30	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A014062	PGDB_C006263	PGDB_AS002434	View
% Degradation	-	=	10	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A014102	PGDB_C006294	PGDB_AS002434	View
% Degradation	-	=	30	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A014460	PGDB_C006273	PGDB_AS002434	View
% Degradation	-	=	70	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A016316	PGDB_C006246	PGDB_AS002434	View
% Degradation	-	=	30	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A017187	PGDB_C006255	PGDB_AS002434	View
% Degradation	-	=	20	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A020742	PGDB_C006286	PGDB_AS002434	View
% Degradation	-	=	60	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A021037	PGDB_C006204	PGDB_AS002434	View
% Degradation	-	=	12	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A022156	PGDB_C006186	PGDB_AS002434	View
% Degradation	-	=	56	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A022236	PGDB_C006183	PGDB_AS002434	View
% Degradation	-	=	30	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A023574	PGDB_C006290	PGDB_AS002434	View
% Degradation	-	=	30	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A023909	PGDB_C006262	PGDB_AS002434	View
% Degradation	-	=	50	%	10 uM	24 h	KRAS	-	-	CN110869369B	PGDB_A023942	PGDB_C006293	PGDB_AS002434	View

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