PatGlueDB | Molecular Glue Patent Bioactivity Database

2D structure

Nc1cccc2nnn(C3CCC(=O)NC3=O)c(=O)c12

Compound summary

Compound IDPGDB_C019789

FormulaC12H11N5O3

Molecular weight273.252

InChIKeyDXZBHVQOULDEPN-UHFFFAOYSA-N

Physicochemical properties

Exact mass273.0862

RDKit cLogP-0.65

TPSA120

HBD / HBA2 / 7

Rotatable bonds1

Heavy atoms20

Hetero atoms8

Rings / aromatic3 / 2

Fraction Csp30.25

Formal charge0

Fragments1

Activity compounds and values

Activity records

15 records

	Control		Value		Concentration	Time					Record ID	Compound	Assay	Details
IC50	-	=	0.0001-0.01	uM	-	—	-	-	HL-60	KR102735378B1	PGDB_A009989	PGDB_C019789	PGDB_AS000015	View
IC50	-	=	0.01-1	uM	-	—	-	-	Tanoue	KR102735378B1	PGDB_A016866	PGDB_C019789	PGDB_AS000293	View
IC50	-	=	0.01-1	uM	-	—	-	-	NALM-6	KR102735378B1	PGDB_A020725	PGDB_C019789	PGDB_AS001071	View
EC50	-	=	0.000000033	M	-	—	-	-	-	AU2020404956A1	PGDB_A021567	PGDB_C019789	PGDB_AS002366	View
IC50	-	=	0.01-1	uM	-	—	-	-	OCI-LY3	KR102735378B1	PGDB_A026252	PGDB_C019789	PGDB_AS000071	View
EC50	-	=	0.000000122	M	-	—	-	-	-	AU2020404956A1	PGDB_A026542	PGDB_C019789	PGDB_AS000822	View
IC50	-	=	0.0001-0.01	uM	-	—	-	-	NB4	KR102735378B1	PGDB_A026680	PGDB_C019789	PGDB_AS000886	View
IC50	-	=	0.01-1	uM	-	—	-	-	MOLM-13	KR102735378B1	PGDB_A034184	PGDB_C019789	PGDB_AS000123	View
IC50	-	=	0.01-1	uM	-	—	-	-	Caco-2	KR102735378B1	PGDB_A040416	PGDB_C019789	PGDB_AS001167	View
IC50	-	=	0.000000703899	M	-	—	-	-	-	AU2020404956A1	PGDB_A048869	PGDB_C019789	PGDB_AS000835	View
IC50	-	=	1-10	uM	-	—	-	-	KG-1	KR102735378B1	PGDB_A057478	PGDB_C019789	PGDB_AS000526	View
IC50	-	=	0.0001-0.01	uM	-	—	-	-	MOLT-4	KR102735378B1	PGDB_A058593	PGDB_C019789	PGDB_AS000194	View
IC50	-	=	1-10	uM	-	—	-	-	TMD8	KR102735378B1	PGDB_A060767	PGDB_C019789	PGDB_AS002232	View
IC50	-	=	0.0001-0.01	uM	-	—	-	-	OCI-LY19	KR102735378B1	PGDB_A070543	PGDB_C019789	PGDB_AS001080	View
EC50	-	=	0.000000698	M	-	—	-	-	-	AU2020404956A1	PGDB_A073570	PGDB_C019789	PGDB_AS000769	View

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