PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberEP4660193A1

AssigneeKorea Research Institute Of Bioscience And Biotechnology Kribb, Korea Research Institute Of Chemical Technology Krict

TitleIndole compound decomposing ikzf2, and use thereof

Family ID92147222

Family members4

Filing year2024

Publication date2025-12-10

JurisdictionEP

Compounds114

Activity records273

Assays4

Activity compounds and values

Activity records

253 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
% Degradation	-	=	6.4	%	1 uM	6 h	-	-	Jurkat	PGDB_A007020	PGDB_C025442	PGDB_AS000451	View
% Degradation	-	=	50.9	%	10 uM	6 h	IKZF2	-	Jurkat	PGDB_A007121	PGDB_C025421	PGDB_AS002037	View
% Degradation	-	=	21.3	%	10 uM	6 h	IKZF2	-	Jurkat	PGDB_A007149	PGDB_C025483	PGDB_AS002037	View
% Degradation	-	=	89.1	%	1 uM	6 h	-	-	Jurkat	PGDB_A007151	PGDB_C025506	PGDB_AS000451	View
% Degradation	-	=	94.6	%	10 uM	6 h	IKZF2	-	Jurkat	PGDB_A007477	PGDB_C025476	PGDB_AS002037	View
DC50	-	<	10.0	nM	-	—	-	-	Jurkat	PGDB_A007668	PGDB_C025525	PGDB_AS001105	View
% Degradation	-	=	21.7	%	1 uM	6 h	-	-	Jurkat	PGDB_A007879	PGDB_C025422	PGDB_AS000451	View
Dmax	-	=	100.0	%	-	6 h	-	-	Jurkat	PGDB_A007927	PGDB_C025524	PGDB_AS000303	View
Dmax	-	=	100.0	%	-	6 h	-	-	Jurkat	PGDB_A008345	PGDB_C025502	PGDB_AS000303	View
Dmax	-	=	96.0	%	-	6 h	-	-	Jurkat	PGDB_A008468	PGDB_C025523	PGDB_AS000303	View
% Degradation	-	=	28.7	%	1 uM	6 h	-	-	Jurkat	PGDB_A009032	PGDB_C025449	PGDB_AS000451	View
% Degradation	-	=	11.8	%	10 uM	6 h	IKZF2	-	Jurkat	PGDB_A009405	PGDB_C025441	PGDB_AS002037	View
% Degradation	-	=	92.6	%	10 uM	6 h	IKZF2	-	Jurkat	PGDB_A009482	PGDB_C025492	PGDB_AS002037	View
% Degradation	-	=	2.4	%	10 uM	6 h	IKZF2	-	Jurkat	PGDB_A009801	PGDB_C025443	PGDB_AS002037	View
% Degradation	-	=	11	%	1 uM	6 h	-	-	Jurkat	PGDB_A010334	PGDB_C025432	PGDB_AS000451	View
Dmax	-	=	100.0	%	-	6 h	-	-	Jurkat	PGDB_A010498	PGDB_C025455	PGDB_AS000303	View
% Degradation	-	=	12.2	%	10 uM	6 h	IKZF2	-	Jurkat	PGDB_A010519	PGDB_C025482	PGDB_AS002037	View
% Degradation	-	=	68.7	%	10 uM	6 h	IKZF2	-	Jurkat	PGDB_A010554	PGDB_C025472	PGDB_AS002037	View
% Degradation	-	=	91.33	%	10 uM	6 h	IKZF2	-	Jurkat	PGDB_A010635	PGDB_C025465	PGDB_AS002037	View
% Degradation	-	=	51.9	%	1 uM	6 h	-	-	Jurkat	PGDB_A011601	PGDB_C025421	PGDB_AS000451	View

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