PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

128 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

E3Not specified

Cell lineJurkat

OrganismHomo sapiens

Technologyluminescence

Detection targetprotein_degradation

Activity compounds and values

Activity records

128 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	=	50.9	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A007121	PGDB_C025421	PGDB_AS002037	View
% Degradation	-	=	21.3	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A007149	PGDB_C025483	PGDB_AS002037	View
% Degradation	-	=	94.6	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A007477	PGDB_C025476	PGDB_AS002037	View
% Degradation	-	=	11.8	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A009405	PGDB_C025441	PGDB_AS002037	View
% Degradation	-	=	92.6	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A009482	PGDB_C025492	PGDB_AS002037	View
% Degradation	-	=	2.4	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A009801	PGDB_C025443	PGDB_AS002037	View
% Degradation	-	=	12.2	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A010519	PGDB_C025482	PGDB_AS002037	View
% Degradation	-	=	68.7	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A010554	PGDB_C025472	PGDB_AS002037	View
% Degradation	-	=	91.33	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A010635	PGDB_C025465	PGDB_AS002037	View
% Degradation	-	=	90.1	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A011724	PGDB_C025496	PGDB_AS002037	View
% Degradation	-	=	-8.8	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A012525	PGDB_C025481	PGDB_AS002037	View
% Degradation	-	=	21.3	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A013085	PGDB_C025446	PGDB_AS002037	View
% Degradation	-	=	78.6	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A013470	PGDB_C025504	PGDB_AS002037	View
% Degradation	-	=	76	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A013955	PGDB_C025463	PGDB_AS002037	View
% Degradation	-	=	50.9	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A015106	PGDB_C025420	PGDB_AS002037	View
% Degradation	-	=	76.2	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A015262	PGDB_C025478	PGDB_AS002037	View
% Degradation	-	=	62.7	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A015693	PGDB_C025438	PGDB_AS002037	View
% Degradation	-	=	33	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A017974	PGDB_C025439	PGDB_AS002037	View
% Degradation	-	=	91.5	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A018388	PGDB_C025512	PGDB_AS002037	View
% Degradation	-	=	1.4	%	10 uM	6 h	IKZF2	-	Jurkat	EP4660193A1	PGDB_A019623	PGDB_C025426	PGDB_AS002037	View

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