PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberUS20200369679A1

AssigneeBiotheryx

TitleCompounds targeting proteins and pharmaceutical compositions thereof, and their therapeutic applications

Family ID71092611

Family members18

Filing year2020

Publication date2023-11-28

JurisdictionUS

Compounds163

Activity records192

Assays9

Activity compounds and values

Activity records

192 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
% Inhibition	-	>=	80	%	1 uM	3 d	-	-	MOLM-13	PGDB_A007024	PGDB_C004432	PGDB_AS001386	View
% Inhibition	-	<	25	%	1 uM	3 d	-	-	MOLM-13	PGDB_A008100	PGDB_C004534	PGDB_AS001386	View
% Inhibition	-	<	25	%	1 uM	3 d	-	-	MOLM-13	PGDB_A008109	PGDB_C004472	PGDB_AS001386	View
% Inhibition	-	>=	80	%	1 uM	3 d	-	-	MOLM-13	PGDB_A008136	PGDB_C004551	PGDB_AS001386	View
% Inhibition	-	<	25	%	1 uM	3 d	-	-	MOLM-13	PGDB_A008372	PGDB_C004507	PGDB_AS001386	View
% Inhibition	-	<	25	%	1 uM	3 d	-	-	MOLM-13	PGDB_A008580	PGDB_C004528	PGDB_AS001386	View
% Inhibition	-	<	25	%	1 uM	3 d	-	-	MOLM-13	PGDB_A008940	PGDB_C004564	PGDB_AS001386	View
% Inhibition	-	=	25-50	%	1 uM	1 h	-	-	-	PGDB_A009129	PGDB_C004436	PGDB_AS000773	View
% Inhibition	-	<	25	%	1 uM	3 d	-	-	MOLM-13	PGDB_A009377	PGDB_C004455	PGDB_AS001386	View
% Inhibition	-	<	25	%	1 uM	3 d	-	-	MOLM-13	PGDB_A009662	PGDB_C004522	PGDB_AS001386	View
% Inhibition	-	<	25	%	1 uM	3 d	-	-	MOLM-13	PGDB_A010163	PGDB_C004484	PGDB_AS001386	View
% Inhibition	-	<	25	%	1 uM	3 d	-	-	MOLM-13	PGDB_A010192	PGDB_C004512	PGDB_AS001386	View
% Inhibition	-	>=	80	%	1 uM	3 d	-	-	MOLM-13	PGDB_A010690	PGDB_C004433	PGDB_AS001386	View
% Inhibition	-	<	25	%	1 uM	3 d	-	-	MOLM-13	PGDB_A011113	PGDB_C004447	PGDB_AS001386	View
% Inhibition	-	>=	80	%	1 uM	3 d	-	-	MOLM-13	PGDB_A011129	PGDB_C004515	PGDB_AS001386	View
% Inhibition	-	>=	80	%	1 uM	3 d	-	-	MOLM-13	PGDB_A011647	PGDB_C004478	PGDB_AS001386	View
% Degradation	-	>=	80	%	0.1 uM	-	IKZF1	-	-	PGDB_A011888	PGDB_C004432	PGDB_AS002410	View
% Inhibition	-	<	25	%	1 uM	3 d	-	-	MOLM-13	PGDB_A012321	PGDB_C004492	PGDB_AS001386	View
% Inhibition	-	<	25	%	1 uM	3 d	-	-	MOLM-13	PGDB_A012880	PGDB_C004523	PGDB_AS001386	View
% Inhibition	-	>=	80	%	1 uM	3 d	-	-	MOLM-13	PGDB_A012917	PGDB_C004489	PGDB_AS001386	View

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