PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberWO2025195464A1

AssigneeShanghai Gdac Biotechnology

TitleSubstituted isoindoline compound, preparation method, pharmaceutical composition and use

Family ID97138372

Family members1

Filing year2025

Publication date2025-09-25

JurisdictionWO

Compounds118

Activity records160

Assays3

Activity compounds and values

Activity records

160 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
DC50	-	<=	0.1	nM	-	—	IKZF3	CRBN	-	PGDB_A007808	PGDB_C011527	PGDB_AS002421	View
IC50	-	<	0.01	nM	-	—	IKZF3	-	MM.1S	PGDB_A007849	PGDB_C011554	PGDB_AS001339	View
IC50	-	<	0.01	nM	-	—	IKZF3	-	MM.1S	PGDB_A008231	PGDB_C011487	PGDB_AS001339	View
IC50	-	=	0.01-0.04	nM	-	—	IKZF3	-	MM.1S	PGDB_A008235	PGDB_C011538	PGDB_AS001339	View
IC50	-	=	0.01-0.04	nM	-	—	IKZF3	-	MM.1S	PGDB_A008582	PGDB_C011461	PGDB_AS001339	View
DC50	-	<=	0.1	nM	-	—	IKZF3	CRBN	-	PGDB_A009385	PGDB_C011499	PGDB_AS002421	View
IC50	-	<	0.01	nM	-	—	IKZF3	-	MM.1S	PGDB_A009878	PGDB_C011467	PGDB_AS001339	View
DC50	-	<=	0.1	nM	-	—	IKZF3	CRBN	-	PGDB_A010442	PGDB_C011541	PGDB_AS002421	View
IC50	-	=	0.01-0.04	nM	-	—	IKZF3	-	MM.1S	PGDB_A010608	PGDB_C011501	PGDB_AS001339	View
IC50	-	<	0.01	nM	-	—	IKZF3	-	MM.1S	PGDB_A010626	PGDB_C011485	PGDB_AS001339	View
DC50	-	<=	0.1	nM	-	—	IKZF3	CRBN	-	PGDB_A011382	PGDB_C011536	PGDB_AS002421	View
IC50	-	<	0.01	nM	-	—	IKZF3	-	MM.1S	PGDB_A012922	PGDB_C011547	PGDB_AS001339	View
IC50	-	<	0.01	nM	-	—	IKZF3	-	MM.1S	PGDB_A013782	PGDB_C011532	PGDB_AS001339	View
IC50	-	<	0.01	nM	-	—	IKZF3	-	MM.1S	PGDB_A014740	PGDB_C011556	PGDB_AS001339	View
DC50	-	<=	10	nM	-	—	IKZF3	CRBN	-	PGDB_A014961	PGDB_C011513	PGDB_AS002421	View
IC50	-	<	0.01	nM	-	—	IKZF3	-	MM.1S	PGDB_A015105	PGDB_C011514	PGDB_AS001339	View
IC50	-	<	0.01	nM	-	—	IKZF3	-	MM.1S	PGDB_A015554	PGDB_C011465	PGDB_AS001339	View
DC50	-	<=	0.1	nM	-	—	IKZF3	CRBN	-	PGDB_A015791	PGDB_C011475	PGDB_AS002421	View
IC50	-	=	0.01-0.04	nM	-	—	IKZF3	-	MM.1S	PGDB_A015871	PGDB_C011521	PGDB_AS001339	View
IC50	-	<	0.01	nM	-	—	IKZF3	-	MM.1S	PGDB_A016424	PGDB_C011507	PGDB_AS001339	View

Rows per pagePage 1 of 8 · 160 recordsGo to page