Assay

PGDB_AS002421

System: cell_basedTarget: IKZF3
Assay context summary

Assay context

55 activity records
Assay family% Degradation
Systemcell_based
ReadoutDC50
TargetIKZF3
E3CRBN
OrganismHomo sapiens
Technologyluminescence
Detection targetprotein_degradation
Activity compounds and values

Activity records

55 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C011527
DC50-<=0.1nM-—IKZF3CRBN-WO2025195464A1PGDB_A007808PGDB_C011527PGDB_AS002421View
2D structure for PGDB_C011499
DC50-<=0.1nM-—IKZF3CRBN-WO2025195464A1PGDB_A009385PGDB_C011499PGDB_AS002421View
2D structure for PGDB_C011541
DC50-<=0.1nM-—IKZF3CRBN-WO2025195464A1PGDB_A010442PGDB_C011541PGDB_AS002421View
2D structure for PGDB_C011536
DC50-<=0.1nM-—IKZF3CRBN-WO2025195464A1PGDB_A011382PGDB_C011536PGDB_AS002421View
2D structure for PGDB_C011513
DC50-<=10nM-—IKZF3CRBN-WO2025195464A1PGDB_A014961PGDB_C011513PGDB_AS002421View
2D structure for PGDB_C011475
DC50-<=0.1nM-—IKZF3CRBN-WO2025195464A1PGDB_A015791PGDB_C011475PGDB_AS002421View
2D structure for PGDB_C011559
DC50-<=10nM-—IKZF3CRBN-WO2025195464A1PGDB_A016856PGDB_C011559PGDB_AS002421View
2D structure for PGDB_C011464
DC50-<=0.1nM-—IKZF3CRBN-WO2025195464A1PGDB_A017059PGDB_C011464PGDB_AS002421View
2D structure for PGDB_C011465
DC50-<=0.1nM-—IKZF3CRBN-WO2025195464A1PGDB_A017500PGDB_C011465PGDB_AS002421View
2D structure for PGDB_C011498
DC50-<=0.1nM-—IKZF3CRBN-WO2025195464A1PGDB_A019550PGDB_C011498PGDB_AS002421View
2D structure for PGDB_C011571
DC50->100nM-—IKZF3CRBN-WO2025195464A1PGDB_A019582PGDB_C011571PGDB_AS002421View
2D structure for PGDB_C011518
DC50-<=0.1nM-—IKZF3CRBN-WO2025195464A1PGDB_A020494PGDB_C011518PGDB_AS002421View
2D structure for PGDB_C011463
DC50-<=1nM-—IKZF3CRBN-WO2025195464A1PGDB_A022714PGDB_C011463PGDB_AS002421View
2D structure for PGDB_C011573
DC50-<=10nM-—IKZF3CRBN-WO2025195464A1PGDB_A024075PGDB_C011573PGDB_AS002421View
2D structure for PGDB_C011562
DC50-<=0.1nM-—IKZF3CRBN-WO2025195464A1PGDB_A026829PGDB_C011562PGDB_AS002421View
2D structure for PGDB_C011540
DC50-<=10nM-—IKZF3CRBN-WO2025195464A1PGDB_A030821PGDB_C011540PGDB_AS002421View
2D structure for PGDB_C011468
DC50-<=0.1nM-—IKZF3CRBN-WO2025195464A1PGDB_A031277PGDB_C011468PGDB_AS002421View
2D structure for PGDB_C011567
DC50-<=10nM-—IKZF3CRBN-WO2025195464A1PGDB_A032162PGDB_C011567PGDB_AS002421View
2D structure for PGDB_C011568
DC50-<=10nM-—IKZF3CRBN-WO2025195464A1PGDB_A033384PGDB_C011568PGDB_AS002421View
2D structure for PGDB_C011459
DC50-<=0.1nM-—IKZF3CRBN-WO2025195464A1PGDB_A033872PGDB_C011459PGDB_AS002421View
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