Activity record

PGDB_A000063

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

DC50 = 45.09 nM

TargetVAV1
Cell line293T-VAV1-FLAG
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS000831
PatentWO2026103873A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031440
Compound IDPGDB_C031440
Compound122;122;化合物 122
Source record IDPGDB_C031440
InChIKeyVFXRDJTWMGMLKM-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000831
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Detection targetprotein_degradation
TargetVAV1
E3Not specified
Cell line293T-VAV1-FLAG
OrganismHomo sapiens

Source evidence

Patent IDWO2026103873A1
Compound location

122;122;化合物 122

122;122;化合物 122 enlarged structure122;122;化合物 122 location on patent page 13
Activity table
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