Activity record

PGDB_A000072

Assay: % DegradationTarget: ARQC: ambiguous
Activity overview

degradation = 79 %

TargetAR
Cell lineVCaP
Concentration50 nM
Assay / Readout% Degradation
Assay IDPGDB_AS001072
PatentWO2026061104A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C030132
Compound IDPGDB_C030132
CompoundAR-P-458
Source record IDPGDB_C030132
InChIKeyULNPCBVBGMLFHZ-UVNRZBLTSA-N

Assay context

Assay IDPGDB_AS001072
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Concentration50 nM
Detection targetprotein_degradation
TargetAR
E3Not specified
Cell lineVCaP
OrganismHomo sapiens

Source evidence

Patent IDWO2026061104A1
Compound location

AR-P-458

AR-P-458 enlarged structureAR-P-458 location on patent page 258
Activity table
Page 269 · table single