Activity record

PGDB_A000104

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

DC50 < 100 nM

TargetVAV1
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001875
PatentWO2026119245A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C032078
Compound IDPGDB_C032078
Compound实施例 5
Source record IDPGDB_C032078
InChIKeyXCXGIHAPKFGVCC-QHCPKHFHSA-N

Assay context

Assay IDPGDB_AS001875
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Detection targetprotein_degradation
TargetVAV1
E3Not specified

Source evidence

Patent IDWO2026119245A1
Compound location

实施例 5

实施例 5 enlarged structure实施例 5 location on patent page 39
Activity table
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