Activity record

PGDB_A000384

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

DC50 <= 20 nM

TargetVAV1
Cell lineprimary_human_blood
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001692
PatentWO2026114367A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031733
Compound IDPGDB_C031733
Compound化合物 160
Source record IDPGDB_C031733
InChIKeySVWWBEPUDQDZID-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001692
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
TargetVAV1
E3Not specified
Cell lineprimary_human_blood
OrganismHomo sapiens

Source evidence

Patent IDWO2026114367A1
Compound location

化合物 160

化合物 160 enlarged structure化合物 160 location on patent page 171
Activity table
Page 204 · table start
Page 205 · table end