Activity record

PGDB_A000531

Assay: % DegradationTarget: KRASQC: standardized
Activity overview

DC50 = 3.6 nM

TargetKRAS
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS002526
PatentWO2026114958A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031978
Compound IDPGDB_C031978
CompoundI-39;I-39;I-39
Source record IDPGDB_C031978
InChIKeyUJYLVBYEVAVCNX-AZUWPLMOSA-N

Assay context

Assay IDPGDB_AS002526
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
TargetKRAS
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-39;I-39;I-39

I-39;I-39;I-39 enlarged structureI-39;I-39;I-39 location on patent page 280
Activity table
Page 287 · table start
Page 288 · table end